Autoimmune Disease

Goodpasture's syndrome

What is Goodpasture's syndrome?

Goodpasture's syndrome is a rare disease that can affect the lungs and kidneys. Also called anti-glomerular basement antibody disease, it is an autoimmune disease-a condition in which the body's own defense system reacts against some part of the body itself. When the immune system is working normally, it creates antibodies to fight off germs. In Goodpasture's syndrome, the immune system makes antibodies that attack the lungs and kidneys. Why this happens is not fully understood. Researchers have identified a number of possible causes, among them the presence of an inherited component; exposure to certain chemicals, including hydrocarbon solvents and the weed killer Paraquat; and viral infections.

Source: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH)

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March is Autoimmune Disease
Awareness Month!

Autoimmune diseases result from a dysfunction of the immune system. The immune system protects you from disease and infection. Sometimes, though, the immune system can produce autoantibodies that attack healthy cells, tissues, and organs. This can lead to autoimmune disease.

Autoimmune diseases can affect any part of the body. More than 80 autoimmune diseases have been identified. Some are relatively well known, such as type 1 diabetes, multiple sclerosis, lupus, and rheumatoid arthritis, while others are rare and difficult to diagnose.

Collectively, autoimmune diseases are among the most prevalent diseases in the U.S., affecting more than 23.5 million Americans. They are more common among women, and while some are more prevalent among white people, others are more common among African-Americans and Hispanics. Autoimmune diseases are becoming increasingly prevalent, for reasons unknown.

Some autoimmune diseases are life-threatening, and most are debilitating and require a lifetime of treatment. There are treatments available to reduce the symptoms and effects from many autoimmune diseases, but cures have yet to be discovered. Since most autoimmune diseases are rare, patients can often spend years seeking a proper diagnosis.

Learn more about autoimmune diseases here.